Main players minutes need to be managed to a 1 game per week basis. That's all. First leg and 2nd leg in CL from now on are 1 week apart. This means not playing in La Liga between these 2 games, and playing just a part in the game before the first leg.
Also, players who didn't play a lot, but have talent should get more minutes. I'm dying to see Todibo. Seen some great bits in those youtube videos with him.
Yet I bet Retardo will use quite a few starters vs. Huesca too