I would like to try something like this
(asymmetrical 4231) MATS---Semedo, Pique, Lenglet, Alba---Busi/Rakitic, Arthur---Dembele, Messi, Bob---Suarez]
I think this lineup has more of a balanced threat from both sides, we can control the game better with Arthur and Bob has the dynamism to cover for Alba whenever he is attacking. Bob would occupy the left half space with Alba on the LW while Messi occupy the right half space and Dembele can take the RW.
Put Alena as a sub for more attacking thrust.